3 Keys for the Rams to beat the Cardinals in Week 10, and set up the rematch

The Rams enter their Week 10 matchup at the Cardinals with momentum, riding a three-game win streak and an opportunity to extend it to four while also avenging a Week 6 loss to Arizona. Kickoff is set for 1:05 p.m. PT on Sunday on CBS.

First, the Rams’ path runs through establishing the run. Ahead of the rematch, Los Angeles’ offense has often taken shape when the ground game is working, including the fact that in four of five wins this season, the Rams rushed for at least 124 yards. The Week 6 meeting featured 92 rushing yards, which the team notes was the second-lowest total of the season (behind a 77-yard effort against the Bills).

Second, Los Angeles needs to limit Arizona’s rushing production. In the Cardinals’ three wins this season, they averaged 146 rushing yards per game, compared with 81 rushing yards in their six losses. The Rams also point to a clear pattern in their own results, noting they have allowed 120 or more rushing yards in three games, including vs. Arizona, and lost all three.

Third, the Rams are aiming to capitalize on a quarterback transition. Arizona is expected to start rookie quarterback Carson Beck in his first regular-season appearance, while the Rams’ preview highlights that the Cardinals’ receiver room is depleted and that tight end Trey McBride remains a central target. On defense, Los Angeles points to its ability to challenge tight ends, including quarterback-routing familiarity from safety Quentin Lake’s prior play against McBride in Week 6.

Together, the game plan centers on a traditional matchup recipe: win the early downs with the run, keep Arizona’s run game from setting up its offense, and create turnovers and pressure that force a rookie quarterback to make mistakes.