Jaguars tackle Anton Harrison set for arthroscopic knee surgery after Week 5 exit

Jacksonville’s offensive line took a hit after Anton Harrison was carted off the field during the Jaguars’ Week 5 victory, and the team’s left tackle is now expected to miss time. Pro Football Rumors reported that Harrison is set to undergo arthroscopic knee surgery, though the period he will be sidelined has not been specified.

Harrison is listed as a fourth-year offensive tackle, and his role matters because the left side is often where an offense tries to establish its protection identity, especially for pass protection against edge rushers and pressure packages. A prolonged absence would force Jacksonville to adjust its starting lineup and the way it builds protection each week.

The immediate practical concern is timing. The Jaguars are scheduled to play a second straight game in London during Week 6, a logistical wrinkle that can complicate practice reps, travel-day routines, and preparation for the next opponent. Harrison, however, is reportedly flying back to the United States as the team prepares for the overseas matchup.

While the injury specifics are limited in the initial report, arthroscopic knee procedures typically require a recovery process that ranges from short stints to longer rehabilitation depending on what is repaired and how the knee responds. With the return window not yet clarified, the Jaguars could face a situation where they need multiple lineup looks and more reps for whoever takes over Harrison’s spot.

Jacksonville’s coaching staff will also have to consider continuity. Offensive tackle reshuffling can affect more than just one position, because line calls, stunts, and slide protections often rely on synchronized footwork and communication. If Harrison misses several weeks, the Jaguars may have to decide whether to keep the line stable with one replacement tackle or to reshuffle across multiple positions to find the best mix.

For Harrison personally, the surgery is at least a concrete next step after the Week 5 exit. The question now is whether his knee will respond on the timeline the team expects and how quickly he can progress from early rehab to full practice. Until that is clearer, his availability will remain a weekly evaluation rather than a firm target date.

The Jaguars’ Week 6 preparations in London will be the first real test of how Jacksonville adapts in the absence of its starting left tackle. How the replacement tackle performs with protection assignments, and whether the team can maintain its pass-protection structure, will likely be the biggest early indicators of how much this injury changes the offense’s weekly ceiling.