Kayla Harrison steps back into the cage with the undisputed bantamweight title on the line against Amanda Nunes at UFC 334

Kayla Harrison’s comeback is set to culminate in her long-awaited matchup with Amanda Nunes, with Harrison putting the undisputed women’s bantamweight title on the line at Polymarket UFC 334 at Madison Square Garden on Nov. 14, according to ’s preview.

The co-main event pairs two of women’s MMA’s defining figures: UFC lists Harrison’s pathway through Olympic-level judo and PFL championship success before she joined the UFC and won the undisputed women’s bantamweight title.

also frames the matchup as the last major box for Harrison in mixed martial arts, casting Nunes as the “returning legend” opponent Harrison must defeat to cement her place at the top of the sport.

Harrison’s preparation is described in the UFC preview as a recovery journey after neck surgery and a lengthy rehabilitation period, and she is quoted saying she has worked back to fighting fitness and is at “100 percent” heading into fight night.

Harrison also discussed how she is thinking about legacy beyond the cage, while reports she has openly spoken about retirement and suggested Saturday night could be her last time fighting, depending on how the moment plays out.