Woman critically injured in multi-vehicle crash in Louisville’s St. Denis neighborhood, police say

A woman was critically injured in a multi-vehicle crash in Louisville’s St. Denis neighborhood, according to a report from WAVE. The initial reports prompted Louisville Metro Police to respond to the 4400 block of Cane Run Road at about 4:52 p.m. on Nov. 5, 2026.

WAVE reported that the crash involved multiple vehicles, though the report did not identify how many vehicles were involved or describe the sequence of events. The report also did not provide details on what caused the collision.

The woman who was injured was described as having critical injuries. The report did not specify her age, her condition beyond “critically injured,” or whether she was taken to a hospital by ambulance.

Police responded to the scene in the St. Denis area, a residential neighborhood on the city’s west side. While the report confirmed the location and the time of the call, it did not describe whether traffic control measures were implemented, whether roads were closed, or how long responders remained on scene.

As of the time of the report, there was no public update included on the status of the other drivers or passengers involved in the crash. The report also did not provide information on citations, arrests, or whether any investigation had identified impairment or violations of traffic law.

A crash investigation typically includes scene documentation, interviews, and review of physical evidence to determine contributing factors such as speed, lane position, vehicle movements, and whether any mechanical issues were present. Officials also may coordinate with fire and emergency medical services to document injuries and response times.